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Feature•Sep 8, 2026

AWS HealthOmics introduces resource fallback order for WDL workflows

AWS HealthOmicsAWS · Machine Learning

Today, AWS HealthOmics introduces the resource fallback directive, enabling you to define an ordered list of preferred accelerator types, including an option to fallback to CPU instances, for tasks in your Workflow Description Language (WDL) workflows. Researchers and bioinformaticians can use this directive to reduce time spent diagnosing and resubmitting runs due to accelerator constraints and keep production workflows running. AWS HealthOmics is a HIPAA-eligible service that helps healthcare and life sciences customers accelerate scientific breakthroughs at scale with fully managed bioinformatics workflows.

With resource fallback, you can prioritize your preferred accelerator for your task. When your preferred accelerator is unavailable, HealthOmics automatically moves through your specified alternatives in the fallback without resubmission. Each accelerator profile has a configurable timeout, giving you control over how long HealthOmics searches for that accelerator before moving to the next. Shorter timeouts help you move quickly through the fallback order, while longer timeouts increase the probability of reserving your preferred accelerator. You can also include a CPU profile as a final fallback to increase the likelihood of your task reserving an instance.

You can now use resource fallback for WDL workflows in all AWS HealthOmics Regions: US East (N. Virginia, Ohio), US West (Oregon), Europe (Frankfurt, Ireland, London), Israel (Tel Aviv), and Asia Pacific (Seoul, Singapore, Tokyo). To learn more, visit the advanced resource configuration documentation.

Read the original announcement↗

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All AWS HealthOmics updates →
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  3. AWS HealthOmics now supports task-level timeout for WDL workflows

    AWS HealthOmics now supports task-level timeout for Workflow Description Language (WDL) workflows, enabling you to set maximum execution duration for individual tasks.

    AWS HealthOmics•Feature•Aug 3, 2026
  4. AWS HealthOmics now available in two additional AWS Regions

    AWS HealthOmics private workflows are now available in the Asia Pacific (Tokyo) and US East (Ohio) Regions, expanding access to fully-managed bioinformatics workflows for research, drug discovery, and agriculture science initiatives with regional compliance requirements.

    AWS HealthOmics•Region•Jul 20, 2026
  5. AWS HealthOmics now supports ephemeral storage for private workflows

    AWS HealthOmics adds ephemeral storage for private workflows, giving bioinformatics workloads dedicated scratch space that delivers more consistent run performance and lower costs.

    AWS HealthOmics•Feature•Jun 23, 2026